I think "The Mandalorian" is as independant from Star Wars as possible, while still remaining Star Wars. It needs you to know only the most basic things - Empire bad. Force mystical. Galaxy Western-like frontier. Everything else - from the familiar aliens like Jawas to EU-stuff like Mandalorians - is only optional knowledge.
A "independant" Star TREK show comparatively would still need you to know the most basic things about Star Trek - warp, beaming, phasers, Klingons, tricorder. That would be a great newcomer show. PIC on the other hand - which I dearly love - needs you to remember Picard, Locutus, Data's sacrifice, Romulan supernova, Hugh, defeated Borg, Tal'Shiar.... That's a whole different level of required backstory. One that's appropriate for a direct sequel (which Picard is). But I also want - in the future - a show that is "as" independant from previous Trek lore as "Mandalorian" is from Wars lore. That is - still filled with lore. But with only the most basic broad strokes required to understand.