AoS does use themes developed from the films but I'm frankly amazed that a few of you aren't grasping that AoS is also building from that foundation by having it's own adversarial group in the form of Centipede. Giving us Deathlok as well.
I know that full well. But I'm not talking about supervillains, I'm talking about themes. I'd also add that they haven't taken this theme from the movies. The only movie that might share the theme I'm talking about hasn't even aired yet. It's an important theme (appropriate for a Wheddon show and for the modern world), but it's one it developed.
I do agree that the show isn't dependent on tie-ins. In fact, they generally don't rely on them at all. Thor was a fun episode, but it didn't change anything. TWS is different, to me, because it centrally focuses on SHIELD. It's hard to imagine no consequences.