Geordi: Congratulations, Data, you just created the Lawnmower Man, er girl.
Picard: Q! What the Hell are you doing?
Q: That Burt Reynolds
Playgirl pose, and if I may say so myself, I nailed it!
Riker: That's right, I'm bringing sexy back.
Q: Hmm, I was expecting...more.
Picard: Troi did tell me she wanted to be a mermaid.
Worf: Sorry, sir, I missed the fly again!
Picard: I'm not asking for much, but this is crap! Where are the Van Goghs? The Picassos? The Kahlos? The Rembrandts?
Troi: The Rembrandts were hunted down and killed after every human being on Earth had "I'll be there for you" stuck in their heads from the 90's to the early 2000's.
Picard: This is all you do? Really? In that case, we're shipping you off to
Deep Space Nine and filling this post with an automated subroutine.
Riker: What do you think, worst charades player, ever?
Data: I served a tour on the refitted Bozeman with Captain Bateson. He kept telling me to put on a red shirt and then laughed.
Doctor: We're ready to perform cardiovascular surgery: the patient is prepped and we've donned the red condom surgeon's attire.
Lt.: Is that a hydrospanner in your pocket, Commander LaForge or are you happy to see me?
LaForge: Both.
Data: If you two are typical for the human population it's amazing your species has evolved to this point.
Dr. Reyga: All I want to do is be respected as a scientist. But, to do that, I've had to forgo profit. I'm basically the most hated person on Ferenginar.
T'Pan: If it is any consolation, you are also the most hated person in this room.