I agree with Picard's decision not to infect Hugh.
Remember, the BORG is entirely made up of beings who have not chosen to be such, but were forcibly assimilated (injected with the Nanites), against their will.
And it was shown several times that beings could be removed from the Collective and still survive, without the need to continue assimilating others.
The only being in the Collective who truly deserved to be nullified was the Queen, as she was the only one who retained her Free Will after being assimilated.
Wiping out the entire Collective without at least trying to save as many as possible, is also Genocide.
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Yeah tell that to the countless trillions in the delta quadrant that would likely get assimilated.
Bet all those are all thankful Picard held by his morals when a cube turns up in their system..........