I'm somewhat surprised that pushing the Eugenics wars 40 years ahead isn't more controversial. Khan himself says that he was exiled in 1996 in Wrath of Khan. Basically all of SNW after Tomorrow and Tomorrow and Tomorrow is basically in a "close enough" timeline ( https://tvtropes.org/pmwiki/pmwiki.php/Main/CloseEnoughTimeline ) and even then there are substantial changes, mainly it's not clear if La'an ever fell for Kirk and that either didn't happen or happened very differently in the original Trek timeline. That's not even getting into the sheer unlikelihood of La'an herself existing as the exact same person with the exact same genome at the exact same time when an ancestor's timeline has been shifted by 40 years (since Khan is still a minor in 2022, the earliest the new timeline Eugenics Wars can take place is in the 2030s, 40 years out from the 1990s, unless he was a teen ruler or something).
And if La'an herself somehow only exists as a descendant of 21st century Khan instead of 20th century Khan that means SNW was never a prequel to TOS to begin with, as presumably then La'an never existed in the original Trek timeline.
And if La'an herself somehow only exists as a descendant of 21st century Khan instead of 20th century Khan that means SNW was never a prequel to TOS to begin with, as presumably then La'an never existed in the original Trek timeline.