Although TNG on TV may have been the height of Trek's popularity, I believe there is little argument that Kirk, Spock and McCoy remain the true cultural icons, even for those too young to have seen TOS. That being the case, in order to try to drum up as much general audience support as they can, whenever a new movie 'series' is launched, it will include Kirk, Spock and McCoy.
My preference would be to avoid another re-boot. Hit the ground running, just like they did with the first ever episode of TOS. There was no need to disclose the 'origin' or original gathering of the crew. Get some writers to come up with some terrific sci-fi ideas and just have them out there exploring.
Again, in keeping with general audience support, there will have to be enough sizzle and pop to address the miniscule attention span of modern audiences, but balance it off with big, thoughtful ideas and character moments.