Even though I've been hyperfocused on the Canonical MCU and am already 3 episodes into my Daredevil Character Marathon, I ended up using the CW App to watch Marvel's Runaways last night (since I don't have anything to occupy my Monday evenings), and, so far through 2 episodes, it's very much reminding me of a combination of the 2017 Power Rangers movie, the Disney movie Hocus Pocus, and DC's Stargirl.
It's also pretty clearly not set in the MCU because the technological levels and overall tone don't fit.
Character-wise, I'm the most interested in Karolina, Nico, Gert, Molly, and Karolina's mom Leslie, but we'll see what happens going forward.