Interesting... She's already played Catwoman, in The Lego Batman Movie. That makes her one of the few people to start out playing a role in animation and then play it in live action. One example is Jeremy Ratchford, who played Banshee in the '90s X-Men animated series and then in the live-action Generation X pilot movie. And of course Kevin Conroy is about to join the club in Crisis on Infinite Earths.
By straddling two universes, I take it you're referring to her role in X-Men: First Class, although she also voiced Mary Jane in Into the Spider-Verse.