Calypso apparently takes place in the 33rd century (Season 3 of Disco happens in late 32nd).
It does not appear to be the same time period.
And Discovery stated it waited in that nebula for about 1000 years.
This could imply more time travel at some point. Perhaps Georgiou going back to participate in Section 31 (upcoming TV series), and leaving Discovery in a nebula for the crew (and having it to continue in advancing itself using the Sphere data - as we've seen, the data already merged with Discovery to prevent itself from being destroyed or deleted).
They may not have had a choice though because I don't understand
Calypso could also take place in the 42nd century. That is to say, roughly 1,000 years after the end of Discovery.