Only retroactively, once we see Agatha's perspective. There is only one blatantly not sitcom thing that happens before that, and its the "beekeeper" at the end of Episode 2 that Wanda attacks. Literally just starting at Episode 4 tells you all you need to know without sitting through badly done boomer nostalgia. I sat through all that and wish I'd known that Episode 4 is the real Episode 1 for the plot.
As for all the people defending the shows, you can like what you like. All I know is that my 60+ year old parents and 89 year old Grandmother didn't like a lot of those shows when they saw them at the time they were made, so the shows aren't as universally beloved by the generations that watched them live as some people here are trying to push. My Mom especially likes some really mediocre sitcoms (she could literally watch King of Queens or Everybody Loves Raymond on a loop all day) and even she can't stand stuff like The Brady Bunch or Leave it to Beaver.
So yeah, I feel totally justified in calling the first three episodes of Wandavision poorly done Boomer bait, parodying shows that don't even deserve to have existed and were garbage even when they originally aired. To be clear, from Episode 4 until the end Wandavision is great, a top 3 MCU show, its just got the worst first three episodes ever.