Who wants to eat junk from a replicator if you can eat fresh foods and cooked?
It's like comparing a genetically modified, chemically laden, microwaved frozen dinner to a an organic chef- prepared gourmet meal.
"genetically modified" means practically nothing. Many of the fruits and vegetables we eat are genetically modified-for example, seeded fruits are modified to be seedless.
Likewise, "organic" doesn't really tell you anything. One can eat "organic" food that tastes awful and is bad for you.
I suspect that those who prefer "non-replicated" food in the 24th century and claim to be able to taste the difference are snobs of the type who think that they can taste the difference between bottled water and tap water. In other words, I'd have them do a blind taste test and see if they could REALLY tell which was replicated and which wasn't.