And this is the real issue, they were raised to believe they were superior and entitled to lead. You don't need to be genetically engineered to turn out an entitled monster if your parents raise you to believe you were born to rule. We see it in real life history and in every day politics to our detriment.
There's your problem, don't raise ANYBODY to think that, that's HORRIBLE and stupid. That entitled snobbish attitude with a superiority complex is what creates tyrants and sociopaths. We don't need that mentality in society.
I think the 1960's view of genetics so close to what happened in the 1930's prejudiced the writers to the concept. We have humans who are physically superior to the average human, we call them athletes. Last time I checked none of the smart athletes wanted to takeover the world
Also, most of our athletes are only great at 1x sport, rarely is it over multiple sports.
And most don't have a Napolean Complex.
Banning someone from Starfleet just because he's too smart is like banning Worf from Starfleet because he's way stronger than any other officer. Worf is stronger, Nog's hearing is maybe as acute as Bashir and Jack's, Troi can read others' minds (and take advantage of this), Spock is better in math than any Human, A'Rex has three hands but that is not and obstacle for them.
But they aren't like Superman from DC Comics, given too many powers or advantages that it becomes a legit possible danger if he ever went rogue / evil.
One or two advantages while other aspects are normal with some vulnerabilities is fine. But stacking too many genetic bonuses or powers together creates too much of a advantage.
e.g. Superman's Kryptonian Bonuses:
PRO(s):
- Flight
- Super Strength
- Super Speed
- Super Durability
- Enhanced Regeneration/Healing
- Heat Vision
- X-ray Vision
- Microscopic Vision
- Telescopic Vision
- Energy generation from Sunlight
- Super Hearing
- Super Breath
- Super Stamina
CON(s):
- Kryptonite
- Magic
It's kind of like the "Team Knight Rider" concept, you don't want one super vehicle, you want some weakness, with lots of strength & the requirement to work together to make you stronger as a group / society.
But nobody should have that many bonuses in one package like Superman.
Most good Japanese Anime/Manga/Light Novels/Shows have a few bonuses at best, and some weaknesses, but never that many powers stacked into one person.
That's just "Too much", it's better to have one or two powers, and develop deep & creative uses of one or two powers than to give too many powers to an individual.
You run into the Superman Writing issue where it's hard to create stories where the super powered being feels like they're in any real mortal danger.