I finished this book about a week ago or so, and have to say that it's found itself a place on my listing of my favorite TNG-related novels (although, admittedly, said list isn't actually that long). I picked it up on a whim after finishing Vanguard: Precipice (primarily because it had Shar on the cover and because, thanks to another thread here, I'd learned that it peripherally dealt with the Tholians, the Shedai, and the Taurus Meta-Genome), and then couldn't put it down.
As someone who hadn't read any of the previous 'TNG Relaunch' novels, this was my first exposure to the Enterprise E's brand-new, post-Nemesis crew, and so several characters were quickly able to catch my attention, most notably T'ryssa Chen and Jasminder Choudhury (I really want to know how to say her name); based on the descriptions of them and their respective roles in PoD, they remind me a lot of two former Enterprise D crewmembers, Tasha Yar and Ro Laren (T'ryssa also reminds me a bit of Jadzia). I also liked the attention that the novel paid to setting up or describing interpersonal romantic relationships for T'ryssa, Choudhury (who would've ever thought that Worf would let himself go again emotionally after what happened with Jadzia?), and Geordi.
Speaking of Worf, the role of First Officer really suits him, not only because it lets him assert himself in typical Worf fashion, but also because it's a great return to all of the things that made him such a great addition to/asset for the crew of Deep Space Nine (particularly given the fact that his tenure on the station resulted in a huge 'black mark' on his career).
I also enjoyed the interaction between Picard and Crusher, and between Picard and his son (Picard as a father and family man is something that I certainly wouldn't have expected, given his history, but is definitely a welcome 'change' for the character); it was also great to see him playing the role of diplomat again, even if his efforts on that front ultimately failed.
It was also great to see Shar again (I haven't yet read Andor: Paradigm, his last pre-PoD appearance), and I really liked the subtle changes in his personality. I do wish he wouldn't have resigned his comission, but completely understand why he did.
Andor leaving the Federation was a ballsy move (both from an in-universe standpoint and from the standpoint of it being ballsy for Dayton to do), and I really liked it; it'll be interesting to see what, if any, future ramifications arise from the situation.
Getting to hear from/see the Tholians again was awesome, especially coming off of having finished Vanguard, and I really enjoyed their role in the story. Personally, I think they ought to be used a lot more frequently than they seem to have been in the past, since they're an extremely fascinating culture, and one whose motives are hard to pin down.
One final thought: PoD, in addition to being an excellent book in its own right, has given me some impetus to read the 'TNG Relaunch', provided I can get my hands on all of the books (if I can't, I'll try to read as much of it as I can), because I really want to see more of/hear more from the Enterprise E's 'new' crew.