A is for the Alpha Quadrant, where most of the known species and civilizations of the galaxy are located.
B is for Bynaus.
C is for Constellation-class Federation starships of the late 23rd and 24th centuries.
D is for the Deltans homeworld. Must be an interesting place to take shoreleave.
E is for the Eymorg.
F is for First Citizen Merikus
G is for Gamma Hydra IV.
I is for Iyaarans.
J is for Jem'Hadar drug addicts.
K is for the Klingon High Council.
L is for LORD Garth, Master of the Universe. Does he know He-Man?
M is for the Mizarians.
N is for Neural Neutralizer.
O is for Optronics.
P is for Positronics.
Q is for Quantum theory that postulates the existence of an almost endless number of parallel universes, some of which were encountered by Enterprise-D tactical officer Worf in 2370.
R is for Redjac. "Die, die, die ...everybody die....ha, ha, ha, ha."
S is for Setlik III.
T is for T'Pol's bum.
U is for United Earth, the world government established in the years and decades leading up to the founding of the Federation.
V is for Vulcan elementary education pods. I guess the Vulcans never heard of slip and fall hazards.
W is for Wesley Crusher.
X is for Xenolinguistics. A field of study that nuUhura is quite "talented" in.
Y is for the Yeager, a Saber-class Federation starship of the late 24th century.