A is for the Altair star system, location of at least two inhabited planets, one of which was home to a spacefaring civilization that had just emerged from a major interstellar war in 2267.
B is for Borg Balls.
C is for Cestus III, settled by the Federation but claimed by the Gorn.
D is for Delta IV, planet of the alopecians.
E is for Eris, the first Vorta ever encountered by a citizen of the Federation.
F is for Fesarius, Flagship of the First Federation.
G is for Gowron, Chancellor of the Klingon High Council from 2367 until his death in combat at the hands of Lieutenant Commander Worf eight years later.
H is for Homework. What the Enterprise engineers frequently reminded Wesley Crusher he had to complete, to get him out of the engineering area so they can actually work.
I is for I.K.S. Gr'oth, the Klingon D7 battle cruiser that visited Deep Space Station K-7. It was commanded by Captain Koloth.
J is for Jonathan Archer. Beagle aficionado.
K is for Kira Nerys, first a major then a colonel in the Bajoran militia and second-in-command aboard station Deep Space 9.
L is for Lantree.
M is for Mugat.
N is for Nelvana III.
O is for Ocampa. For them, a week is a long term commitment.
P is for Phase cannons.
Q is for Quasar-like phenomena.
R is for Radar, the 20th century American military version of which detected the Enterprise 1701 high in Earth's atmosphere in July of 1969.