I have also learned by living in male dominated world that there will always be at least one man to interrupt what you are saying, so I just raise my voice and continue talking or openly say "I'm not done talking" or something similar.
Our IS department is about a 75/25 split though it's wildly spread across different sub-disciplines. The manager of the largest group is female though. - As for being interupted, I like the line one of my colleagues used "Pardon me for talking while you're interrupting". That tend to shut people up rather nicely

(ETA - one of my colleagues was mentioning earlier that her daughter was the only female in her University IT course though and it does seem a common thing in STEM courses unfortunately).
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