Absolutely regarding the 'broad' movies, but it's down (as far as I am concerned anyway) to internal consistency and the suspension of disbelief.I find the Guardians movies and Thor: Ragnarok pretty broad and implausible in their storytelling, if that's what you mean by "cartoony." I mean, they have a talking raccoon, tree, and duck in them. And the physics in the MCU have always been absurd, ever since Tony Stark survived crashing into the desert at rocket speed inside a rigid metal suit. It shouldn't matter whether it's live-action or animation. Especially since so much of the "live-action" these days is computer animation anyway, so the distinction between the two is becoming increasingly irrelevant.
Some of the stuff in the MCU would take me right out of a Trek movie if it happened there. And some Trek stuff would pop my disbelief if it happened in an Alien or hard sci-fi movie. It's all very specific and relative.
Animated offerings in a live action franchise are already straining at that by being visually very, very different. I'm already at the far edge of my suspension of disbelief. If the content of that animation drags it any further, my disbelief is no longer suspended.
Edit : I was fine with all manner of crap in the Indy movies, even (barely) exiting a plane in a life raft, but the nuclear fridge incident was way out there and lost me.