No, that was Smallville. This is generations earlier on a different planet. There couldn't be any familiar Superman villains except maybe versions of Zod or Brainiac. Like I said, this feels more like Caprica.
I would include Mongul and Warworld as part of the Superman rogue's gallery. But I would hope they farm DC's interstellar characters and worlds for more fodder. DC's first mutant, Captain Comet took to he stars in the late 50s. He could come across Krypton. The Dominators are out there, as are the Khund. Or DC's Vega system aliens could come by. They can explore why no other races came to aid Krypton in its time of need. Just because the Kryptonian on the street didn't believe Jor-El, doesn't mean other races didn't see what was happenng to Krypton.