The Alcubierre drive is the example usually quoted. Supposedly there is now a design that doesn't require negative energy. The curvature of space-time within a solar system is relatively flat except near massive bodies such as stars and planets. The curvature required by the drive's warp field is probably large in the vicinity of the wall of the warp bubble where large tidal forces would be experienced. However, the whole concept is not something that I know much about. Even the experts often disagree about what is and isn't possible. Even if it isn't possible to construct such a drive, knowing exactly why it's impossible would provide valuable understanding of Physics.
This is good, though, because if you can only travel easily in flat space-time, with gravity being a barrier, it means that there's a reason we're not suddenly wiped out by an alien fleet. That's a fair trade off.
Heh. In Star Quest Online, to jump from Hyperdrive I to Hyperdrive V, some genius got the idea of...getting out of the system first, past the solar influence (which was around the Asteroid belt, Arbitrary) and boom. Gravitational bodies being a sort of 'coast' or 'seabed' is more than fine. Sure a Star Destroyer can't just pop out over D.C, but that's a fair trade, isn't it?
Post-9/11 we now know that accident isn't the only source of danger. Having our beautiful Star Trek dream hijacked by radicals could have disastrous consequences.
Having it hijacked means at worst they burn it up on a course that might take it over a city. Space throws worse at us every day, and while atmospheric distribution will not be enviable, it'll be a fraction of a fraction of any atmospheric bomb test we've done.
We need to stop being so damn scared of nuclear power, nuclear accidents, nuclear mishap. Fukushima did not kill the Pacific, Chernobyl did not kill Kiev to its south, Three Mile didn't do jack. It's all overblown. Respect nuclear, manage it properly, yes, but it's not a world-ender.