JiNX-01 said:
Enterprise:
Connor Trinneer: Captain Charles "Trip" Tucker III and
Jolene Blalock as T'Pol, his wife and a civilian scientist aboard NX-01 (they met when he trained aboard a Vulcan ship in anticipation of his mission).
Nathan Fillion: Commander Michael Kenmore

, First Officer. He quit Terra Prime because he disagrees with the move toward violence to achieve their goals, but still harbors resentment toward non-terrestrials.
Dominic Keating: Lt. Malcolm Reed, Tactical/Security. An agent with S31, he has been instructed to secretly pursue information on a new species called Romulans, who appear to be making preparations for invasion. Tucker won't learn of this until 2 years into their mission.
Linda Park: Lt. Hoshi Sato, Linguist/Protocol. She's a descendent of a genetically enhanced soldier from the Eugenics Wars, benefitting from enhanced intelligence that allows her to quickly learn new languages. She is drawn to Reed because she also has an inate gift for tactical challenges and will even help out on occasion (much to his delighted surprise

).
John Billingsley: Dr. Mark Gibson, Chief Medical Officer. Participated for 2 years in the interspecies medical exchange. He won't get along with Kenmore because of the bigotry.
Jewel Staite: Julie Reynolds, Physician's assistant/EMT. A bit of a fish out of water, she was backup PA/EMT, but the original crew member is killed in an accident shortly before launch. She's curious about aliens but also nervous and uncomfortable around them. T'Pol is particularly mysterious and it will take a long time for Reynolds to warm up to her.