From the actors suggested...it seems like they're going the Ultimate Fantastic Four route.
Most of the recent Marvel movies have drawn elements from the Ultimate universe, or done similar things -- Galactus as a cosmic swarm, the Hulk's origin being linked to supersoldier serum, Nick Fury looking like Samuel L. Jackson, etc. Which makes sense, since both the Ultimate Universe and the movies are attempts to reinvent the Marvel universe with more modern sensibilities, to filter out some of the sillier, more dated, or more problematical aspects of the original works.