Someone once claimed that the international public tends to g for more intellectual films instead of the big hollywood action blockbusters, but that's not true. Wolverine has almost 48% overseas gross, and Fast & Furious even 54%!
The movies that tend to have a large proportion of foreign vs domestic box office are the ones that are simple and require little or no backstory to understand. Americans might be reading
X-Men or watching
TOS but you can't expect that to be as common elsewhere.
Star Trek is a very complex story that traditionally has required some serious backstory to grasp.
Something like
Fast & Furious does extremely well overseas because there's no backstory worth mentioning. But to Americans, that's not a big brand name they already recognize and know the backstory for, so they aren't going to be unusually motivated to go see it, versus
Star Trek, where they've already invested a fair amount of time and understanding, or at least know of it from pop culture references. Being immersed in the culture probably does make the difference here: Americans know who Kirk and Spock are, even if they don't care about
Star Trek.
Oh, and I think it has nothing whatsoever to do with the fact that Star Trek is American centric. Almost 100% of the movies in German theatres are from the US. So I think this argument is pretty moot.
I have a hard time seeing how
Star Trek is more American than say
Terminator, which is about a bunch of Americans fighting killer robots who technically speaking, are also Americans since that's where they were manufactured.

What the hell could be more American than a bunch of grubby people in foxholes battling gigantic robots in a noisy and explosion-filled manner?
Last year's Indiana Jones movie was unusually heavily skewed towards foreign BO, 40/60 (usually it's more like 50/50 for summer blockbusters) and that was about a retro Cold War scenario pitting heroic Americans vs eeeeevil Russkies that would make Boris and Natasha Badanov look subtle by comparison.
Compare that with with
Star Trek and its no-money, no-religion, no-national-divisions, let's-all-sing-kumbayah hippie commie shit.

Downright un-American!
Who in Asia or Europe has heard of "Lost?" or J.J. Abrams?
Can't speak for Asia, but I'd say you
greatly underestimate the success of
Lost in Europe.
Lost is one of the most popular TV shows in the world, right up there with
CSI: Miami, or so I've heard.
With all those viewers maybe somebody can figure out what the frak is going on.
I'm going to say that only the USA (and Japan for their local stuff) have populations of nerd/geeks large enough to sustain a success for a science fiction film.
Sci fi films tend to do very well globally (which is why we get so many of them). From last year,
The Dark Knight was 53/46 and
Iron Man was 54/45.
Hancock was 36/63 (someone explain that one to me!)
Wolverine is 53/47. Yet
Star Trek is now at 71/29, way out of step with other movies in its genre. Maybe the foreign BO will come up, but so far it's not following the same trend as you'd normally expect.
Also, please, have in mind that in most countries, admittance price is not as ridiculously high as you are used to. For that kind of money you Yanks pay for one ticket, I get two tickets here.
Isn't it possible this could be a factor in lower box office numbers as well?
Why is only
Star Trek affected by the price of tickets and not all the other movies?