I can't speak for a lot of other people, but I am almost positive that my brother, who is literally one of the people Isaacs is talking about and refuses to watch Discovery because of Burnham and the relationship between Culber and Stamets (my brother is anti-gay marriage, pro-Brexit, and sees "political correctness" everywhere--practically the opposite of me in every sense), is going to despise the Picard show.
He thinks he will like it because what he calls "politically correct" elements aren't immediately obvious from the trailers, but he hasn't actually bothered to read what Patrick is actually saying in interviews/appearances or the prequel comic books that came out. I think he's in for a surprise when he watches the show.