Another interesting question, should this cartoon adhere to or just ditch past continuity, in order to appeal to a younger audience?
One has to keep in mind, that kids today wouldn't know about some of the stuff we grew up with when Star Trek when it was really popular, like the TNG Borg stories or the Klingon/Romulan drama stories, the Khan vs. Kirk struggle, etc.
I'd be fine with it being in a separate continuity, but that's not the only way to avoid confusing people. Two things can be in the same reality but still work as distinct, standalone stories. All you have to do is not let continuity porn drive your show the way Discovery too often does. I mean, TNG in its early seasons tried to avoid TOS references as much as possible, outside of "The Naked Now." It was in the same universe (more or less), but it told its own stories rather than constantly referring back to old continuity.