Good thoughts. Though, do we even know that the Vulcanian, Romulan, Betazoid, and Klingon cross-breeds were conceived normally? I personally prefer the theory that half-breeds we see required some sort of scientific aid.
ENT: "Demons"/"Terra Prime" did confirm that a human-Vulcan hybrid child would require medical and genetic intervention to achieve. And DS9 said it "wouldn't be easy" for a Trill and a Klingon to have a child, implying the same. On the other hand, there have been cases of hybrids apparently being conceived "by accident," like Alexander and Ziyal.
About Orion Animal Women, I prefer the depiction of them in the original script of "The Cage"...
This depiction is much more compelling than that of a sexy dancing girl, or the godawful Enterprise pheromones-power play crap. Here they're more like sirens. They're wild animals that lure men to their deaths. Only occasionally can they be tamed...for...you know.
I wouldn't call that "compelling," I'd call it misogynistic. A desirable woman as an animalistic beast? Female allure as a lethal temptation for men? That's steeped in Roddenberry's generation's sexual hangups and centuries of cultural demonization of female sexuality. Considering that Roddenberry's own treatment of the women who worked on his shows would be unlikely to pass muster in the MeToo era, the recurring tendency in his work to blame women for being irresistible creatures luring good men astray (see also Nona, Ilia, and the opening narration of his 333 Montgomery Street pilot with DeForest Kelley) comes off as making excuses for his own sexual excesses.
My theory, which you are free to disregard, is that the seeding experiment by the aliens in "The Chase" actually failed. Their efforts to direct evolution failed, becasue evolution doesn't work like that. Only one of the species on a planet actually evolved to resemble the "The Chase" species and that was homosapiens and their ancestors. Then as I mentioned up thread some as yet unknown alien force transplanted these species from earth throughout the galaxy. These transplants were genetically modified to adapt them to local conditions and make them compatible with local life. So basically all human looking species were descended from humans. The Tkon, Sargon's people, Cardassians, Klingons, AD INFINITVM; were all genetically modified humans taken from earth at various points in history.
That doesn't add up, since Sargon's people were colonizing the galaxy well before Homo sapiens evolved. 600,000 years ago, our ancestors would've still been H. heidelbergensis, capable of controlling fire and using primitive tools, but not yet capable of humanlike speech and not yet creating art or abstract symbols.
Of course evolution in real life doesn't work the way Star Trek portrays, but neither does relativity, quantum physics, temporal physics, force field dynamics, linguistics, etc. Humanoid aliens, like warp drive and universal translators, are a deliberate break with reality for the sake of the narrative. It works that way in the story, regardless of how it works in reality.