At this point, I would be cool with it if they ended "Rebels" as is and re-launched it as "Rebellion" or somesuch, and then told stories with a wider scope similar to "Clone Wars". Assuming that one season = one year, we are now almost two years pre-ANH. At this point, there is surely a wider array of Rebellion stories than can be told than through the lens of the same Rebel cell over and over and over again. Don't abandon the Ghost crew altogether, as there are still plenty of stories to be told there, but a new format would allow them to branch out a little.
The likely focus of a theoretical "Rebellion" show would be a newly-promoted General Syndulla. With the rank, comes a wider array of responsibilities. This would allow the narrative to branch off into the adventures of other characters. For instance, history has shown that Star Wars fans eat up stories about Wedge Antilles, and lo and behold, there he be! Wedge and Hobbie could be under the General's command and have stories focused on them. Cassian Andor and K-2SO seem like an natural fit for an arc (anything for more of Alan Tudyk 's K-2SO). The history of Jedha could be explored with Chirrut and Baze. I think that there is at least one more Saw Guererra story to be told between his appearance in Rebels and Rogue One. What? Did someone say Han and Chewie? Even if they can't get Harrison Ford, I bet the new guy would do it.
Yeah. I would seriously watch that show.