Just a few ideas i've had bouncing around my head about what I would want in a NEW Mass Effect game. I'm also going with the assumption that as a game, Andromeda is dead. As flawed as it was, I actually really enjoyed MEA, but if there is to be any continuation to that series, I assume it will only be in novel or comic form. I'd love to be wrong about this. But anyways, fully expecting Bioware to go back to the well that is the Milky Way as well as sticking to their guns and not canonizing any one ending, a prequel or "sidequel" is the only option. I would have the game begin a few years before ME1 and have the game span the entire timeline of the trilogy right up to the ending. Perhaps your protagonist could be the captain of a relatively small freighter, something akin to the Falcon or Serenity and you could follow the lives of you and your ragtag crew as you deal with the various events of the trilogy while also obviously influencing your own storyline, independent of the trilogy. You could have tension with aliens because of hard feelings over the first contact war, family killed at Eden Prime, encounters with Geth and Collectors, and even deal with how a simple freighter crew deals with the Reaper war. You could even end with an epilogue based on which ever choice your Commander Shepard made and finally show us all what life was like in the Milky Way after picking up the pieces of the war. There is something I just like about seeing the world from "the other side". If you think about it, in all 4 games you play as a character with a military backround and a fully functional, pretty much brand new ship. You are well funded and have the backing of either a galactic government or a powerfull organization. Now just imagine being on the other side of that. You work only for yourself and your crew, just trying to get buy. Your home port isn't the shiny and bright Citadel but the dark and dirty Omega. Your ship isn't some top of the line Military Frigate or Scout ship, but instead some well lived in, barely holding together, converted freighter. You're not a criminal mastermind, just a man or a women trying to make his way in a galaxy that doesn't give a damn you exsist. Maybe I'm too much of a Firefly fan or something, but this appeals to me. Anyways, just an idea I've had kicking around my head for awhile.