In TMP it seems as though Kirk does slight Dr. Chapel in the scene after Spock mind-melds with V'ger, onboard the Enterprise in Sickbay. Kirk responds to Dr. Chapel as though he is speaking down to her or at her instead of to her, he does not even look at her while he is responding to her question. This may have been staged this way so the actress got paid less under SAG rules, or Bill Shatner may have been trying to upstage Majel Barrett-Roddenberry, or it may have been Director Robert Wise's decision to stage that scene that way, I don't know.
Here is the script excerpt courtesy of http://www.dailyscript.com/scripts/startrek01.html
Interestingly enough, the one Star Trek tv script on that site is "What Are Little Girls Made Of?"