In the Best of All Possible Worlds, I'd of liked of 7 movies, each focusing on a different crew member. The series did this, after all.
The point of movies is to show what you can't in half the time and a fraction of the budget, so I would have taken all the BIG things we'd ever want to see, and just Star Wars Matrix LotR-ified them. I'd have done a huge Borg invasion movie. BoBW was the single ship, this time they send thousands, like locusts overrunning everything. But in the best tradition of TNG, it would be about the exploration of grand themes - which only gives more weight to the kewl adventure story. Collectivism vs. individuality explored smartly, honestly, and in depth. And at some point, a trip inside the hive mind.
Also a huge Dominion War movie showing why the Federation flagship wasn't leading the assault on the enemy's homeworld yet still shows why it is THE flagship. ...Say it wasn't at the tail end of the war because it was in repairs after the fleet it headed defeated the Tholians after they, like the Breen, entered the war on the wrong side.
How about revisiting and tieing up loose ends from the series...there could be a huge "Conspiracy" movie, a huge final Romulan-Vulcan reunification movie, a huge Nagilum and "Emergence" movies.
Certain things would happen also that we'd always waited for like Riker and Troi getting married, Picard and Crusher getting together, Data creates a working positronic android... Oh, and we get to see Shuttlebay 1 and Cetacean Ops!