^ After that suggestion I feel awful making this post but...
I would build a Trek themed hotel. My goal would be to create an immersive experience for the guests. I don't want a hotel with Trek components. I want to do reproductions of famous ships or places that just happens to be a hotel. I have been wanting to do this for years. I have even done sketches and floor plans for it!
First, I would have six different wings with interiors designed to look like six different aspects of Trek: TOS Enterprise, Movie Enterprise, New Movie Enterprise, Enterprise D, Voyager and NX-01 Enterprise. The guest rooms would be designed to either mimic an ensign, officer, captain or admiral's quarters. The first two would be on the "inside" of the "ship" with no windows. The last two would feature windows with a moving starscape outside that would periodically go to "warp" or visit a nebula or show the ship orbiting a planet. Each wing would have hallways and elevators that look like the corridors and turbolifts from the ship it represented. All six wings would feature a reproduction of that ship's bridge and reproductions of key sets scattered around on the other floors. (The Movie-E and Enterprise D would even have a multi-level engine core!) The wings would be connected in the middle by a restaurant/lobby/conference/gift shop building done as a reproduction of DS-9 with functioning "airlocks" seperating the "starbase" from each wing. I would also ask Paramount to throw in some simulator rides and a Trek museum to round out the package. Employees would be dressed in costume to match the area they are working and we would also encourage guests to do the same.
This thing would cost a HUGE amount of money (45 to 40M?) to do. But with enough convention space for Cons, a great location and permission/franchise from Paramount, I think this thing could really do some decent business and the promotional ideas are endless. My biggest issue right now with idea is size. To big and you loose money on the building and keeping staff. To small and you choke yourself out of the larger conventions.