Of the three Trek shows that went seven seasons, I think that DS9 was the only one that maybe should have done an eighth.
* Move some of the S7 Ezri shows to later. More shows about her adjusting to a haphazard joining.
* The Ezri/Bashir romance develops more slowly, and maybe the viewers actually give a rat's a** about it.
* Worf stays on DS9. He is promoted to commander and made Kira's first officer. He and Kira periodically squabble over how things should be run.
* Have Sisko return to his family in time to greet his and Kassidy's child, ultimately retiring to Bajor, his work finished.
* Bajor gets a Kai who isn't Nurse Ratched, and finally joins the Federation.
* We see changes in the Dominion, courtesy of Odo. Exploration of the Gamma Quadrant resumes... but they keep the Defiant handy!
* The Federation aids Cardassia in the largest relief effort in galactic history.
* The Romulans find out about the whole "In the Pale Moonlight" thing. And they're pissed.
* Ferengi hardliners try to undo all of Zek's reforms.
* Certain crew return to the Mirror Universe one last time, and take steps to prevent the Evil Terran Empire 2.0 from arising from the Terran rebellion.