It certainly seems to be the case, but there is nothing saying that Carl didn't miss when he shot her. As someone else said, he could have closed his eyes, pulled the trigger and ended up just grazing her.
Oh, for the love of God...
Kirkman has said she's dead. Executive Producer
Greg Nicotero (who directed the last episode) has said she's dead.
SHE'S DEAD. SHE WAS KILLED BY CARL AND HER REMAINS WERE EATEN BY THAT ZOMBIE.
SHE'S NOT JUST RESTING.
SHE IS NOT STUNNED.
SHE'S NOT JUST PINING FOR THE FIORD.
SHE IS DECEASED!!!!!
Lori Grimes the character has ceased to be! She's expired and gone to meet her maker! She's a stiff! Bereft of life, she rests in peace! Pushing up the daisies! Her metabolic processes are now history! She's off the twig! She's kicked the bucket, she's shuffled off 'her mortal coil, run down the curtain and joined the bleedin' choir invisibile!!
Geezus.