I wonder what the prospects are for bringing back the rest of the cast from the live-action series. It's been 13 years since that series, and all four leads are in their 40s, ranging from 42 for Liz Vassey to 49 for Patrick Warburton. That's not a dealbreaker, since three Avengers (Downey, Ruffalo, Renner) are in the same age range. But Hollywood's standards for actresses are narrower (Scarlett Johansson is the youngest Avenger at 29), so I fear Vassey might be considered too old to reprise her role. And Nestor Carbonell's currently a regular in Bates Motel, and seems to be pretty busy overall, so he might not be available.
Actually that might be an interesting dimension for the new series -- to focus on the issues superheroes face as they get older and start to slow down or get overshadowed by the young upstarts. Sort of a Justice Society angle.