So 1 person is supposedly a "Natural Born" Human Telepath out of countless Billions that have come & gone who were not.
No; again, "Where No Man..." established that many humans had low-level esper abilities and that there was a standardized test for determining an individual's "
esper rating."
KIRK: And you, are you feeling all right?
DEHNER: Yes. Mitchell, too, except for his eyes. We're trying to find a reason for that now, and why, out of our whole crew, only certain people were affected.
SPOCK: I think we've found that answer, Doctor.
KIRK: You mentioned that tests show you have a high degree of extrasensory perception. So do the records of the others. Gary Mitchell has the highest esper rating of all.
"The others" in that passage are the
nine crewmembers who were killed by the barrier passage. That means that eleven members of the
Enterprise crew had some esper ability, with only Mitchell and Dehner being strong enough espers to survive the barrier. That's eleven out of a few hundred, maybe 1 in 40 if we assume the crew complement is closer to the series's 430, 1 in 20 if it's the same crew size as "The Cage." That adds up to hundreds of millions if the crew is a statistically representative sample. (Which didn't fit my theory in
The Higher Frontier, so I had to handwave it that the Duke-Heidelburg [sic] esper rating test gave a lot of false positives.)
Of course, that was only asserted in that single episode, and Miranda was the only other human telepath we ever saw. But if you're determined to insist that canonical information is "fact" rather than just mutable storytelling, it's self-contradictory to ignore the information presented in the second pilot.
It's also absurd to believe that only one human out of countless billions would have telepathy. It's enormously more probable that if Miranda Jones has such strong telepathy (even surpassing Spock's), then other humans would have the potential to a lesser degree. After all, no potential comes out of nowhere. It has to arise from existing evolutionary foundations. The rare blood type you mention is a poor analogy, because it's just a slight variation in the proteins and sugars coating red blood cells. It's not a unique sense or ability that nobody else has, just a unique configuration (as far as we know) of molecules that are part of everybody's blood cells. Mutations are like that. They don't manifest entire new superpowers out of nowhere like in comic books; they're just slight tweaks on our existing genetics. It takes quite a few generations of successive slight tweaks for a major change to occur.