Anyway.... This particular YouTuber brought up the fact that in Prodigy, which I haven't seen yet, Janeway commands a vessel with a QSD, based on the Dauntless design. And he speculated that with QSD being part of a functioning ship build by Starfleet in 2383 I believe, that it might be possible that the Enterprise F in Picard might be outfitted with one as well.
I personally doubt this will happen, but it would open up a whole new galaxy to play with for any spin-offs of Picard, should they want to do more shows set after it. 25th century show that has the capacity to easily travel to the DQ, GQ. And don't forget, a lot of the AQ and BQ is still unexplored. Space is big.