Both Transformers and Harry Potter will almost certainly make more money the Star Trek.
I can take or leave HP. Waited for DVD for all of them. But when I saw the trailer in the theater this weekend (when I was easily talked into a 3rd Trek viewing), it looks damn good, more than a little dark, and likely to pull a lot of fence sitters into the theater much the way the Trek trailer did. I don't do the box office prognostication thing, but HP looks to make money but the wheel barrel full.