I know I trot this out every now and then when this topic comes up, but I'll say it again. I'd be curious to explore the road not taken: an animated series picking up after "The Cage." Tweak the characters and add some new ones. There's a decades worth of stories before the Kirk era. Marvel Comics' Early Voyages was an interesting experiment giving us a glimpse into that era and more could be done. An advantage is that "The Cage" characters are largely blank canvases since we only saw them once so you wouldn't have to think about reinterpreting established characters. Even Spock---the lone familiar character---would be in state of evolution from his younger days. You also wouldn't have to worry about aesthetics in terms of production standards because "The Cage"/TOS would be ideal for animation. One writer I think could be interesting to contribute a story or two would be John Byrne. His TOS stuff for IDW Comics is usually quite good. C'mon, CBS, make it happen.