Would this have made her? Some mystical being who had mysteriously managed to overcome the insurmountable limits of "human failing" centuries, if not millennia in advance, or simply a person whose sexual orientation fortunately suited the situation?
I'll say it one more time, because i've said it a few times already, i'll package it slightly different this time.
To answer the direct question, Bi Crusher may or may not still answer it the same way. The issue was not entirely "Odan is a woman now", it's "Odan keeps changing people, and now he turned into something incompatible". Bi Crusher may have found it easier to adjust, but given that even when Odan had taken Riker as a host she was already having issues dealing with it, it may be the same exact answer.
But, if she didn't care and the issue was entirely, 100% the "gay" issue then... her experience would be different, given her sexual orientation, and she probably would not answer it the same way, being a part of the small percentage of the population who would be compatible.
Another person not in that with that same experience may well likely say "humanity...", since the overwhelming majority of humans are heteronormative and that would be that persons experience, but since that term is used in context of a generalization, also in absolutely no way whatseover invalidates any human who may be able to love in such a way.
I don't know how many different ways I can say it. So. There ya go.
tl;dr just to bring it home, "humanity" does not literally mean every single possible individual who lived, lived or ever will live while specifically stating that anyone who does not fall under the generalization is in some way inhuman or nonexistant.
I'm tired, boss.
I actually thought that this was what was being mocked by the QWERTY thing, the ever-changing acronym and flag. Personally I thought it kind of funny and I say that as someone represented by the B.
I wish more people were like you.
I also appreciate the mockery, but I understand such things are often done/said in a deragatory manner making fun of the people themselves, not the situation of "LGBT-Idontknowwhatotherletterstousebecausetheresomanynow".
I wouldn't write that myself. But I can appreciate the humor in it.
EDIT -
I wanted to add one last thing that I think making Crusher say "i'm not gay sorry" or thereabouts would not work.
The point is that she loves Odan, the "spirit" inside the shell. She loves the mind, the personality, etc. of the consciousness of Odan.
Crusher was hoping that one day, humanity could love beyond the physical shell, to not even see it. The only thing that matters is the essence of the person.
Are there some people who could? I'm sure. But now you're talking a percent of a percent.
Her specifically calling out an LGBT issue could almost be ANTI-LGBT in a way... she's saying that the physical body shouldn't matter. It's a limitation of humans that it does. And that's true, unless you're saying that lesbians should just look past, and date cis men because it's what's inside that counts, and gay men should date cis women because the physical body shouldn't matter...
No. That's just not the case, that's not human nature. The body does matter, in some way. Differently to different people, but it does. It matters. It's human.