What wrong there?Where in the universe is it OK to hit on your best friends 21 year old daughter?
Kirk was about 13 years older than the girl and McCoy some 10 years beyond Kirk. So just from an age point of view everything's fine. McCoy has a younger friend.
Kirk and Joanna developing a romance isn't quite the same as Kirk "hitting on her." It's not like he was going to be slipping a roffie into her chocolate milk.
Unless you're going to have McCoy be one of those fathers who can't accept that their offspring in now an adult.
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I figure past is prologue. The relationship Kirk develops with Joanna McCoy, however it is characterized and labeled, would probably be no different from the other relationships Kirk develops with women throughout the series. I'm not sure if Kirk was "hitting on" Lenore Karidian or if it "romance." But Joanna would probably be just more of the same--whatever it is.