Star Trek is about as bomb-proof as you can get in the entertainment business. It is such a diverse franchise, really incomparable. TV series, films, games, books, merchandise. Only Star Wars has a similar breadth, but as great as those films are, TV is God in the modern world. Film is big, but if you're on TV, you are everywhere.
So I agree with other posters who have stated that TV is where its at for Trek. I don't think the new film can make or break it. It can give it a Klingon hypo-spray, and hopefully spark a new series. Or it might be mediocre. I doubt it will be bad.
Look - Insurrection faltered, Nemesis bombed, Enterprise got tanked, and here they are making a new film. This franchise of Star Trek is like an Omega Particle.
I think that the vital signs of Star Trek can be seen in whether it is on TV. DVDs are obviously available, but still, I think as long as one or more of the series is currently on, Trek lives.