Suppose the voyage took 75 years, then most of the primary crew would have been around 105, some slightly younger, some somewhat older.
Do we have any information how "old"105 would be in the 24th century ? We know O'Brien is told he will yet die an old man at age 140 in his bed, we see McCoy at age 137 being extremely geriatric, so it's safe to assume that 140 is a very advanced age. But 105?
The only example that comes to my mind right now of that age range is that of the Bajoran judge Els Renora (from "Dax"), whom we are told is 100 and she is still active at work (even though she looks distinctly 'late middle age' to me). But she's Bajoran, not human ...
In the first season of DS9, the episode "Dax":
Station log. stardate 46910.1. Chief O'Brien has escorted his wife back to Earth to celebrate her mother's hundredth birthday. In the meantime, the rest of us are trying to keep the station up and running.
In the fifth season episode "The Darkness and the Light":
KIRA: Well, since Keiko's visiting her parents with Molly, I guess there's room.
So both of Keiko's parents were alive approximately four years after Keiko's mother's 100th birthday. Note that it is quite usual for a husband to be a few years older than his wife.
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