Perhaps, but you'd also want to try to capture the zaniness and screwball-comedy aspects or what's the point?
A LOWER DECKS novel should not read like a mainstream TREK novel. It should read like a LOWER DECKS novel.
I think the two aren't that far apart and not because I write zany off the wall screwball comedy novels w/ dramatic elements. Well, not just.

I was actually inspired to write genre comedy (and write in general) because of New Frontier.
NF combined camp and serious(ish) dark storytelling in equal measure. I could easily see the novelized version working just as well.