Perhaps a bit too clever, a bit too "Frasier," but I absolutely loves this scene from "The Circle:"
KIRA: Come in.
ODO: You're not?
KIRA: Leaving? I really don't have much choice, do I
ODO: You're not just leaving, Major. You're surrendering.
KIRA: You break the rules, you pay.
ODO: Wait a minute. I want to be sure I heard that correctly. Because it doesn't sound like the Kira Nerys who has made a career out of breaking the rules.
KIRA: Well, I guess I broke one too many.
ODO: Major, you've been breaking one too many for fourteen and a half years. Cardassian rules, Bajoran rules, Federation rules, they're all meaningless to you because you have a personal code that's always mattered more. And I'm sorry to say you're in slim company.
KIRA: I'll miss you too, Odo.
ODO: Have you asked Sisko for help?
KIRA: I'm sure he'll do whatever he thinks is best for the station.
ODO: You haven't even gone to him?
KIRA: Well what do you want me to do, Odo?
ODO: Fight for what you want. It's what you do best.
KIRA: Maybe I just want a vacation.
ODO: Idiotic bureaucracy. Now I suppose they'll expect me to break in a new man.
KIRA: A great man. Li Nalas can handle the job, believe me.
ODO: You did fairly well at it once I smoothed your rough edges.
KIRA: Ha!
ODO: What's so funny?
KIRA: I thought you did fairly well, once I smoothed your edges.
(doorbell)
KIRA: Yes?
DAX: Am I disturbing anything?
KIRA: Stick around, you can help me cry in my synthale.
DAX: I thought I'd better return this epidellic lotion.
KIRA: No, if you like it
DAX: Oh, it's wonderful.
KIRA: Well then, keep it.
ODO: How can you be chatting about skin lotion at a time like this?
(doorbell)
DAX: Do you have any idea where you'll be stationed?
KIRA: Come in. Not yet. They say that after I've taken some leave time, I've earned a desk at the foreign affairs building somewhere. Doctor.
DAX: Foreign affairs building?
BASHIR: I came to give you my best.
DAX: Well that's rather dull.
BASHIR: I beg your pardon?
KIRA: Dull is a polite word for it.
ODO: Doctor, if you were Kira, wouldn't you at least be complaining to Commander Sisko?
BASHIR: Look, I just wanted to wish you good luck.
KIRA: Thank you, Doctor.
BASHIR: Complaining about what?
ODO: Never mind, Doctor. If she doesn't care, why should we?
BASHIR: Have they given you any reason yet?
DAX: Did they give you any alternative?
KIRA: I do care. No, they haven't. No, they didn't. I really ought to finish packing.
(doorbell)
BASHIR: You said she doesn't care. You mean about leaving
KIRA: By all means, come on in.
(O'Brien enters)
ODO: She's done well here. She ought to stay here. And I'd say she needs a little support from her friends, Doctor.
BASHIR: Well, yes, certainly, but if her orders
O'BRIEN: Er.
KIRA: Chief. Come in.
O'BRIEN: I didn't mean to intrude. I just
BASHIR: Don't worry, Chief. It's all been said.
ODO: I have a good deal more to say, thank you, Doctor.
O'BRIEN: Look, I could come back.
DAX: Odo, leave her alone. This is Kira's decision to make. Unless of course you want me to talk to Sisko.
KIRA: I knew what I was doing. I knew the risk.
ODO: That's not what she asked.
O'BRIEN: I'd just like to say, Major, it's been a pleasure serving with you.
(doorbell)
KIRA: Come in.
BASHIR: Will somebody please explain this conversation to me?
QUARK: A party! For you, I would've reduced my catering rates.
ODO: It's not a party.
QUARK: Whatever.
ODO: What's that?
KIRA: A bottle of my favorite synthale, I think. That's very thoughtful, Quark.
ODO: It's also very small.
QUARK: I was anticipating a far smaller gathering. I thought, perhaps, an intimate farewell drink, a sympathetic smile, a shoulder to cry on.
O'BRIEN: As I was saying, Major
QUARK: You'd be surprised how often that works with women.
KIRA: Is this a joke? Did you plan this?
BASHIR: Nobody could have planned this.
(doorbell)
KIRA: We're open for business. Come on in. Join the crowd. Vedek Bareil.