Well the Galaxy Trio could work as a live action series, I can see it in the TOS universe timeline, or set within the Next Generation setting, with the Crew being part of Starfleet or more appropriately part of the Federation Police force. They could tone back the superhero aspects, and yet still retain the feel of a superhero team, all while fighting crime in the Federation territories and worlds within Federation space. Instead of explorations, there are tons of planets, ancient aliens sleeping underground, or invaders in outer colonies, and so on that could work for that as a TV series. It could also include villains similar to a Harry Mudd, or finding some ancient alien tech on a colony world where people have gone missing. a pretty much overall story arc of policing the federation, with the Galaxy Trio as the primary crew.. Space Ghost however would seem a bit of a stretch, unless he was dealt with like a Batman character, and was either a Soon type android, or some kind of human who acquired the Space ghost mantle with some sort of lost alien tech found by him.. either way, I still think the basic Idea of Galaxy Trio would be perfect for fitting into the Startrek universe. impulse engines, and warp capable could also fit the Condor ship, however I took a different route with the tech for my schematics.
Another interesting idea I had been thinking about was placing the Dune series in with the Chronicles of Riddick series. Dune the movie would be more appropriate, but it would fit with how Riddick was done. That would be the Earthen side of the Padishar Imperium. The propulsion tech from Riddick was on the outskirts of the empire, while the inner planetary spheres were using the large jump ships and the spice to fold space. the pioneers outlands were the furthest from the central battles with the Major Houses. I'd love to see something there.
As for Waylan, it could work with Firefly for sure. I rather like the Dark Matter series myself. I can see Firefly working there too.. along with the expanse. Not sure about the series with the former hobbit.. Name escapes me.. Kill Joys I think?? that could also work in firefly and Dark Matter I think.. haven't seen killjoys yet, so not sure.. any thoughts?