I'd still like to see what's going on with the Klingons and Ferengi, not because I want the drama to focus around them, but because there's just no reason not to capitalize on existing worldbuilding to tell a better story. They told a good story with Nevar and Trill, and there's tons of creative opportunity in extending other races hundreds of years into the future. Just as long as they are the setting for a part of the story, and not the entire story.
They should find that line where they are capitalizing on all the existing worldbuilding and lore to make new stories better. Not ignoring the previous worldbuilding completely, or being so stuck in it that it turns into fanservice.
There's no need to go to Bajor because they're pretty much strongly spiritual humans anyway, although it'd be rewarding to see Bajor and Cardassia as best friends now.
The result of the Temporal Cold War has already pretty much been revealed. The Federation won, the timeline was stabilized and they illegalized time travel.