I think it could work for them generally speaking, but there does come a point when the MCU has gone to this well too many times. Cap frozen in the arctic, Bucky and Zola experimented on by Hydra, Star-Lord abducted by aliens, Ant-man's secret cold war career, Captain Marvel off somewhere in space. Is it really worth it to add the negative zone to that list? But if so, then at least give them something different. Not the 90s. The 60s are a good aesthetic for the F4's jetson-esque brand of sci-fi. Or forget the 'they're from the past' shtick and make them the MCU's first parallel universe heroes.