I liked it. I has a bunch of similarities to Fables, but there are enough differences.
I never watched House much, but Jennifer Morrison was very good as the lead character (her reaction in the bathroom to the kid showing up was very affecting). Ginnifer Goodwin and Joshua Dallas were good as Snow White and Prince Charming (I like that they're largely playing the latter straight; it's pretty common to try and deconstruct him, as with Fables, and while that's fun, it can get dull too).
The production values were pretty good for TV.
The guy playing Rumpelstiltskin was creepy, but I kept thinking that he was too tall. I can see why they did that (they want a physical presence), but I thought he's always been represented as a little person.