So, a re-tread of Spider-Man 3, but with one fewer villain? The Batman Returns method (villains team up to take down the hero) has been run into the ground ... and it generally sucks, in the first place.
I believe Mr. Light was suggesting that Black Cat and Spiderman would team up to take down Lizard, not Lizard and Black Cat (any movie Lizard would probably be feral and not particularly into team-ups anyway). Reading it now, though, it doesn't make much sense; what would Black Cat have to gain taking out the Lizard? Spiderman, sure, out of respect to Dr. Connors, to save any innocents the Lizard might harm, and of course to-rescue-Mary-Jane-whom-the-Lizard-kidnapped-because-he-smelled-his-emeny-Spiderman-on-her. The villain should be somebody who can have a motive that Black Cat could find abhorrent or counter to her own interests, and wish to eventually foil.
Fictitiously yours, Trent Roman