Well, I've been a Khan naysayer, but if Orci and Kurtzman are as serious as they say they are:
I'd trust that they'd find an OK way to do Khan. I still hope it's not in the next film.
"I'm already going back and reading some of the books I've missed," he said of "Trek" tales and fan-fiction that have been written in past years, which could be reinterpreted for their new universe. "I'm trying to read every 'Star Trek' book I can get my hands on. We did that a lot for the first movie. ... I'm starting to re-immerse myself again in what's come before."
I'd trust that they'd find an OK way to do Khan. I still hope it's not in the next film.