Yes, I can imagine quite a few scenarios along those lines:
- The aliens have discovered the secret of near immortality but are unwilling to share it.
- The aliens have discovered the secret of near immortality and are willing to share it.
- The aliens have discovered how to tap zero-point energy but are unwilling to share it.
- The aliens have discovered how to tap zero-point energy and are willing to share it.
- ...
- The aliens have discovered all the secrets of the universe but are unwilling to share them.
- The aliens have discovered all the secrets of the universe and are willing to share them.
Contact with superior intellects could produce a global gestalt of apathy and nihilism. Even acquiring their knowledge would either make us very dangerous to ourselves and to them or make us feel very inadequate. That's if they don't just decide to exterminate us to remove a potential threat and steal our stuff.
Three quotes by A C Clarke come to mind:
"Two possibilities exist: either we are alone in the Universe or we are not. Both are equally terrifying."
"I'm sure the universe is full of intelligent life. It's just been too intelligent to come here."
"One day we shall meet our equals, or our masters, among the stars."